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About us

The UCL School of Pharmacy is one of the UK’s leading centres of pharmacy education and research it enjoys a lively and stimulating academic environment in which teachers, researchers, professionals and students interact. All are connected by an interest in medicines - how they work, how they are made and how they are used by people to prevent and treat disease. Research focuses on advancing and understanding medicines and health care, and in creating new medicines. The Clinical Pharmacology & Therapeutics Group, within the Department of Pharmacology is one of the few research groups in Europe with expertise in clinical drug development, repurposing and evaluation of benefit-risk balance and effectiveness of medicinal products, including evidence generation by modelling and simulation technologies. Its interdisciplinary nature aims to attract and integrate professionals and researchers from different fields, ensuring different perspectives and innovative solutions are identified for translation, optimisation and personalisation of pharmacological interventions in the target patient population. Further information on the main research topics in the group can be found at: https://profiles.ucl.ac.uk/19796-oscar-della-pasqua.

About the role

• The clinical pharmacology research fellow will lead the activities and coordinate the efforts for the implementation of extrapolation methodologies for paediatric diseases. • Ensure scientific and clinical pharmacology-related activities are aligned with the overall project objectives as well as pre-defined deliverables. • Develop drug-disease models and simulation scenarios supporting the extrapolation of efficacy across diseases based on the credibility framework. • Travel between London and Belgium, France and Italy for workshops and face-to-face meetings with other consortium members. The post is available until 30 September 2027 in the first instance. • This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa • We will consider applications to work on a part-time, flexible and job share basis wherever possible.

About you

You will have a PhD in bioengineering or similar relevant discipline (e.g., clinical pharmacology, pharmacometrics, systems pharmacology, biomedical engineering, PKPD modelling). Working knowledge of nonlinear mixed effects modelling principles and Bayesian statistics. Working knowledge and hands on experience with pharmacometrics software tools, in particular NONMEM and MONOLIX Experience with (clinical) population pharmacokinetics and pharmacokinetic-pharmacodynamic modelling, and in particular with the analysis of antibiotics and paediatric data. Working knowledge of clinical pharmacology principles, GCP and regulatory guidelines regarding the requirements for the evaluation and approval of paediatric medicines.

What we offer

As well as the exciting opportunities this role presents we also offer some great benefits some of which are below: 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days) Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan On-Site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance Visit https://www.ucl.ac.uk/work-at-ucl/rewards-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/